The term " cytochrome p450 " first appeared in literature in 1962 . it was a microsomal membrane - bound hemoprotein without known physiological functions at that time and was characterized by a unique 450nm optical absorption peak of its carbon monoxide - bound form 細(xì)胞色素p450這一術(shù)語最早于1962年被用于描述一種結(jié)合微粒體膜的未知其功能的膜蛋白,因其在450nm處有一特征吸收峰而得名。